Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 701-171-0 | CAS number: -
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
The genetic toxicity of TSP/DSP was tested in a bacterial reverse gene mutation assay on S. typhimurium strains (RBM study No. 970075, 1997), using both plate incorporation and pre-incubation methods. This Ames test was a key study of validity 1 according to Klimisch cotation criteria.
The test substance showed no mutagenic activity up to the limit concentration of 5000 µg/plate in the presence or absence of mammalian metabolic activation.
Therefore, the test item was considered non mutagenic in the Ames test.
Short description of key information:
No in vitro mutagenic activity
Endpoint Conclusion: No adverse effect observed (negative)
Justification for classification or non-classification
Due to the absence of induced mutant colonies over background in an Ames test up to the limit concentration of 5000 µg/plate in the presence or absence of mammalian metabolic activation, no classification is warranted for mutagenicity.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
