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EC number: 453-570-1 | CAS number: 540734-22-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Similar to OECD Guideline 203, GLP, key study, validity 2:
96h-LC50 = 13.1 mg/L (95% CL: 11.1 - 15.6 mg/L), based on nominal concentrations.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 13.1 mg/L
Additional information
One key study is available to assess the acute toxicity of the substance to zebra fish (Brachydanio rerio). This study was performed similar to OECD Guideline 203 with GLP statement. Based on the results of the preliminary test, the definitive test was conducted with the test concentrations of 5.0, 7.5, 11.2, 16.7 and 25.0 mg/L (nominal concentrations). Concurrent water control group was performed in parallel. The study was performed with a semi-static water renewal system.
The 96h LC50 was calculated as 13.1 mg/L (nominal concentration), and the 95% confidence limit was 11.1 mg/L - 15.6 mg/L. The highest concentration without observed effect was 5.0 mg/L.
All validity criteria of the OECD Guideline 203 were not fulfilled as no information is available on the analytical measurements. Based on the analytical measurements of the other aquatic studies (algae and aquatic invertebrates) and that this study was conducted in a semi-static system, there must be evidence that the concentration of the substance has been satisfactorily maintained. Therefore, this study is considered reliable with restrictions.
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