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Endpoint summary

Additional information

Acute valid data, based on international guidelines, are available for three trophic levels: Algae Aquatic Invertebrates and Fish; and on Microorganisms. These data are summarised in the table below:

Level of exposure / trophic levels	Test substance	Organism	EC50/LC50	EC10/NOEC	Flag / reliability	Performing laboratory	Reference in IUCLID
Acute / Aquatic algae	Registered substance	Desmodesmus subspicatus	72h: 20 mg/L (growth rate)	72h: 11 mg/L (growth rate)	K/2	Harlan	Toxicity to aquatic algae and cyanobacteria, 2008, Goodband, RS, K
Acute / Aquatic invertebrates	Registered substance	Daphnia magna	48h: 15 mg/L	-	K/2	Safepharm	Short-term toxicity to aquatic invertebrates, 2008, Goodband, RS, K
Acute / Fish	Registered substance	Brachydanio rerio	96h: 13.1 mg/L	-	K/2	Supervision and Test Center for Pesticide Safety Evaluation and Quality Control	Short-term toxicity to fish, Zhao, 2008, RS, K
Acute / Micro-organisms	Registered substance	activated sludge	3h: 700 mg/L	3h: 180 mg/L	K/2	Safepharm	Toxicity to microorganisms, 2008, Clarke, RS, K

Among data available, the fish, Brachydanio rerio, is the most sensitive species with a 96h-LC50 at 13.1 mg/L. For aquatic invertebrates, the 48h-EC50 was determined at 15 mg/L. For algae, the 72h-EC50 value was determined at 20 mg/L (based on growth rate). For microorganisms, the 3h-EC50 and 3h-NOEC values were determined at 700 mg/L and 180 mg/L respectively.