Registration Dossier
Registration Dossier
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EC number: 453-570-1 | CAS number: 540734-22-3
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Hazard for air
Hazard for terrestrial organisms
Hazard for predators
Additional information
Environmental fate and pathways:
The substance is not considered readily biodegradable (43% biodegradation after 28 days) and based on the hydrolysis study, is stable with a half-life at 179 days at pH 7. The adsorptioncoefficient (Koc) of the substance was estimated, based on a weight of evidence approach using experimental and QSAR results, at 624 L/kg, corresponding to a log Koc at 2.80.This result indicates that the mobility class in soil is low (according to P.J. McCall et al., 1980).
Ecotoxicological information:
Acute valid data, based on international guidelines, are available for three trophic levels: Algae, Aquatic Invertebrates and Fish; and on Microorganisms.
Among data available, the fish, Brachydanio rerio, is the most sensitive species with a 96h-LC50 at 13.1 mg/L. For aquatic invertebrates, the 48h-EC50 was determined at 15 mg/L. For algae, the 72h-EC50 value was determined at 20 mg/L (based on growth rate). For microorganisms, the 3h-EC50 and 3h-NOEC values were determined at 700 mg/L and 180 mg/L respectively.
Conclusion on classification
No harmonised classification is determined for the substance.
Based on data available, the lowest EC50 is comprised between 10 and 100 mg/L (96h-LC50 = 13.1 mg/L, Brachydanio rerio) and the substance is not considered readily biodegradable with a log Kow at 3.92.
Classification according to the Annex VI of the Directive 67/548/EEC: The substance is classified as R52/53 for the environment.
Classification according to the Annex VI of the Regulation (EC) No 1272/2008 (CLP): According to the 2nd ATP, the substance is classified as Aquatic Chronic 3 for the environment.
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