Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 261-245-9 | CAS number: 58430-94-7
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
The substance was found to hydrolyse under environmental conditions. The hydrolysis reaction did not follow pseudo-first order reaction kinetics. The rate of the hydrolysis reaction was dependent on the starting concentration and was decreasing with decreasing concentration.
Key value for chemical safety assessment
Additional information
A valid hydrolysis study in accordance with OECD TG 111 was conducted. The results of a preliminary test indicated that further testing is required and the hydrolysis was studied in a main test at pH 4, pH 7 and pH 9 with sample solutions being maintained at 50, 60 or 70 °C at pH 4 and 7 and at 40, 50 and 60 °C at pH 9. It was found that the substance did not follow pseudo-first order reaction kinetics. The substance hydrolysed under all test conditions and the rate of reaction was dependent on the starting concentration. The rate constants for the reaction at 25 °C were estimated by using the Arrhenius relationship and were 15.8 (g/L)^-1.5 per hour at pH 4, 3.45 (g/L)^-1.5 per hour at pH 7 and 0.0154 (g/L)^-0.25 per hour at pH 9. This corresponds to a half-life of 4.49, 20.6 and 6.85 days at an initial concentration of 8 mg/L and of 142, 650 and 12.2 days at an initial concentration of 0.8 mg/L.
The results of the study show that abiotic hydrolysis of 3,5,5-trimethylhexyl acetate may contribute to the degradation of the substance in the environment, but that the importance of the hydrolysis is significantly depending on the starting concentration of the substance and the environmental conditions.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
