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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: inhalation

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Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
1942
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Data reported in the database ChemIDplus.

Data source

Reference
Reference Type:
secondary source
Title:
Unknown
Author:
National Defense Research Committee
Year:
1942
Bibliographic source:
National Defense Research Committee, Office of Scientific Research and Development, Progress Report Vol. NDCro 132, Pg.Aug. 1942. Cited in ChemIDplus; http://chem.sis.nlm.nih.gov/chemidplus/

Materials and methods

Principles of method if other than guideline:
Unknown test guideline.
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Dimethyl maleate
EC Number:
210-848-5
EC Name:
Dimethyl maleate
Cas Number:
624-48-6
Molecular formula:
C6H8O4
IUPAC Name:
dimethyl (Z)-but-2-enedioate

Test animals

Species:
mouse

Administration / exposure

Route of administration:
inhalation

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
other: LC
Effect level:
> 1 500 mg/m³ air

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
The lethal concentration of DMM in mice was reported to >1500 mg/m³.
Executive summary:

The lethal concentration of DMM in mice was reported to >1500 mg/m³.