Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 210-180-4 | CAS number: 609-15-4
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 30 March 2010-22 June 2010
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: This study has been performed according to OECD and EC guidelines and according to GLP principles.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 010
- Report date:
- 2010
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- Ethyl 2-chloroacetoacetate
- EC Number:
- 210-180-4
- EC Name:
- Ethyl 2-chloroacetoacetate
- Cas Number:
- 609-15-4
- Molecular formula:
- C6H9ClO3
- IUPAC Name:
- ethyl 2-chloro-3-oxobutanoate
- Details on test material:
- - Name of test material (as cited in study report): Chloracetessigester
- Molecular formula: C6H9ClO3
- Molecular weight: 164.59
- Substance type: Clear slightly yellowish liquid
- Physical state: liquid
- Analytical purity: 93.9%
- Impurities (identity and concentrations): -
- Composition of test material, percentage of components: -
- Isomers composition: -
- Purity test date: -
- Lot/batch No.: 001008
- Expiration date of the lot/batch: 26 July 2010 (retest date)
- Stability under test conditions: Stable
- Storage condition of test material: At room temperature in the dark
- Other: -
Constituent 1
Study design
- Analytical method:
- high-performance liquid chromatography
Results and discussion
Partition coefficientopen allclose all
- Type:
- log Pow
- Partition coefficient:
- 1.2
- Temp.:
- 20 °C
- pH:
- 7
- Type:
- log Pow
- Partition coefficient:
- 1.2
- Temp.:
- 20 °C
- pH:
- 1
Applicant's summary and conclusion
- Conclusions:
- The HPLC method was chosen for the determination of the partition coefficient of Chloracetessigester. The Pow and log Pow value of the major peak in the chromatograms of the test substance are: 1.5 x 10E1 and 1.2, respectively (at both neutral pH and pH 1.0)
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
