Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
eye irritation
Remarks:
no data
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: database entry

Data source

Reference
Reference Type:
review article or handbook
Title:
Eye irritation rabbit
Year:
2008
Bibliographic source:
National Technical Information Service, Springfield 22161, Formerly U.S. Clearinghouse for Scientific and Technical Information OTS0528440

Materials and methods

Principles of method if other than guideline:
no data
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
2,6-diisopropylphenyl isocyanate
EC Number:
248-885-4
EC Name:
2,6-diisopropylphenyl isocyanate
Cas Number:
28178-42-9
Molecular formula:
C13H17NO
IUPAC Name:
2-isocyanato-1,3-bis(propan-2-yl)benzene

Test animals / tissue source

Species:
rabbit
Strain:
not specified

Test system

Vehicle:
not specified
Controls:
not specified

Results and discussion

In vivo

Results
Remarks on result:
other: only databaze entry, no details

Applicant's summary and conclusion

Interpretation of results:
highly irritating
Remarks:
Migrated information Criteria used for interpretation of results: EU