Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 204-278-6 | CAS number: 118-79-6
Toxicity to terrestrial arthropods
Administrative data
Link to relevant study record(s)
Description of key information
Geuijen (2001) was considered adequate and reliable for use in assessing the toxicity of 2,4,6-tribromophenol in terrestrial arthropods. The study was performed to both OECD guideline 213 and 214, the study was also GLP compliant.
Key value for chemical safety assessment
Additional information
Reference: Geuijen, W.H.C. (2001)
Reliability: 1
Results: Some mortality was observed in the contact test with tribromophenol in the honey bee (<10%), however, this was less than the level of mortality observed in the solvent control. Mean Abbott corrected cumulative mortality was 0% at all doses. Contact LD50 was concluded to be above 100 ug/bee. The NOEC was set at the highest tested dosage, i.e. 100 ug/bee.
Dosing orally, tribromophenol induced some mortality (<10%). At the highest tested dosage (actual dosage 112 ug/bee) mortality was 7% after 48 hours. There was no mortality in the solvent control. Hence, the oral LD50 for Tribromophenol is above 112 ug/bee. The NOEC was set at the highest tested dosage, i.e. 112 ug/bee.
Duration |
Endpoint |
Effect conc. |
Nominal/Measured |
Conc. based on |
Basis for effect |
Remarks (e.g. 95% CL) |
96 h |
NOEC |
100 µg per animal |
nominal |
test mat. |
mortality |
Contact test |
96 h |
LC50 |
> 100 µg per animal |
nominal |
test mat. |
mortality |
Contact test |
48 h |
NOEC |
112 µg per animal |
nominal |
test mat. |
mortality |
Oral |
48 h |
LD50 |
> 112 µg per animal |
nominal |
test mat. |
mortality |
Oral test |
The following information is taken into account for effects on soil arthropods for the derivation of PNEC:
Geuijen (2001) was considered adequate and reliable for use in assessing the toxicity of 2,4,6-tribromophenol in terrestrial arthropods. The study was performed to both OECD guideline 213 and 214, the study was also GLP compliant.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
