4,8-Dimethyl-2,5,7,10-tetraoxaundecane

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

GLP compliance:

yes (incl. QA statement)

Type of method:

flask method

Key result

Water solubility:

> 26 - < 27.9 other: %w/w

Conc. based on:

test mat. (total fraction)

Temp.:

20 °C

pH:

4.5

Details on results:

The standard EC A.6 / OECD 105 methodology was not applicable to this test item due to its very high solubility. Therefore, testing was carried out by visual appraisal.
It was evident from data relating to the pH of the test item in water that negligible hydrolysis of the sample solution occurred during the course of the test.

After preparation, the samples were shaken at approximately 30 °C for at least 72 hours. After standing at 20.0 ± 0.5 °C for a period of 24 hours, the samples were visually appraised. The pH of each solution was measured (where possible).

Sample	Concentration (% w/w)	Observations	Solution pH
1	10.2	Clear, colorless solution, free from excess test item.	7.5
2	20.0	Clear, colorless solution, free from excess test item.	7.2
3	29.5	Cloudy solution with excess test item.	6.8
4	39.6	Cloudy solution with excess test item	6.5
5	22.1	Clear, colorless solution with no excess test item. No change on agitation.	5.9
6	24.1	Clear, colorless solution with no excess test item. No change on agitation.	4.9
7	26.0	Clear, colorless solution with no excess test item. No change on agitation.	4.5
8	27.9	Clear, colorless solution with no excess test item. However, on agitation, the sample became cloudy.	Not performed due to the cloudiness of the sample

Conclusions:

The water solubility of 4,8-dimethyl-2,5,7,10-tetraoxaundecane has been determined to be in the range 26.0 to 27.9% w/w of solution at 20.0 ± 0.5 °C.

Executive summary:

Water Solubility of 4,8-dimethyl-2,5,7,10-tetraoxaundecane is in the range 26.0 to 27.9% w/w of solution at 20.0 ± 0.5 °C by visual assessment, using a procedure designed to be compatible with Method A.6 Water Solubility of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 105 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.

Description of key information

The water solubility of 4,8-dimethyl-2,5,7,10-tetraoxaundecane has been determined to be in the range 26.0 to 27.9% w/w (approx. 350 to 390 g/L) of solution at 20.0 ± 0.5 °C.

Key value for chemical safety assessment

Water solubility:

370 g/L

at the temperature of:

20 °C