Registration Dossier
Registration Dossier
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EC number: 636-728-6 | CAS number: 24690-44-6
Skin sensitisation
Administrative data
- Endpoint:
- skin sensitisation: in vitro
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- publication
- Title:
- QSAR Toolbox prediction for single chemical
- Year:
- 2 021
- Bibliographic source:
- QSAR Toolbox 3.4.0.17
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: QSAR Toolbox 3.4.0.17
- Version / remarks:
- Database version: 3.8.8/3.1.2
- GLP compliance:
- no
Test material
- Reference substance name:
- (4R)-4-[(4S)-2-oxo-1,3-dioxolan-4-yl]-1,3-dioxolan-2-one
- EC Number:
- 636-728-6
- Cas Number:
- 24690-44-6
- Molecular formula:
- C6H6O6
- IUPAC Name:
- (4R)-4-[(4S)-2-oxo-1,3-dioxolan-4-yl]-1,3-dioxolan-2-one
- Test material form:
- solid
Constituent 1
Results and discussion
In vitro / in chemico
Results
- Run / experiment:
- other: QSAR
- Parameter:
- other: Skin sensitisation II (ECETOC)
- Vehicle controls validity:
- not applicable
- Negative controls validity:
- not applicable
- Positive controls validity:
- not applicable
- Remarks on result:
- no indication of skin sensitisation
- Other effects / acceptance of results:
- The prediction is based on 5 neighbours' values, 3 of them equal to prediction.
Prediction confidence is measured by the p-value = 0.500 (no confidence)
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
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