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Diss Factsheets

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2021

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
GLP compliance:
no
Other quality assurance:
ISO/IEC 17025 (General requirements for the competence of testing and calibration laboratories)
Type of method:
flask method

Test material

Constituent 1
Chemical structure
Reference substance name:
(4R)-4-[(4S)-2-oxo-1,3-dioxolan-4-yl]-1,3-dioxolan-2-one
EC Number:
636-728-6
Cas Number:
24690-44-6
Molecular formula:
C6H6O6
IUPAC Name:
(4R)-4-[(4S)-2-oxo-1,3-dioxolan-4-yl]-1,3-dioxolan-2-one
Test material form:
solid

Results and discussion

Water solubility
Water solubility:
4.144 g/L
Conc. based on:
test mat.
Incubation duration:
72 h
Temp.:
20 °C
pH:
4.5

Any other information on results incl. tables

In the three determination results, the absolute value of the relative difference between each two samples is less than 15%; therefore, the three determination results are valid.
Take the average [(4.041+4.143+4.249)×10-3/3] g/mL= 4.144 g/L as the measurement result, and also indicate pH = 4.5.

Applicant's summary and conclusion

Conclusions:
Water Solubility is 4.144 g/L (20 ℃, pH=4.5).