Registration Dossier
Registration Dossier
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EC number: 211-322-8 | CAS number: 638-16-4
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- disregarded due to major methodological deficiencies
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
Data source
Reference
- Title:
- Unnamed
- Year:
- 1 977
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- GLP compliance:
- not specified
- Test type:
- other: only one dose tested
Test material
- Reference substance name:
- 1,3,5-triazine-2,4,6(1H,3H,5H)-trithione
- EC Number:
- 211-322-8
- EC Name:
- 1,3,5-triazine-2,4,6(1H,3H,5H)-trithione
- Cas Number:
- 638-16-4
- Molecular formula:
- C3H3N3S3
- IUPAC Name:
- 1,3,5-triazine-2,4,6(1H,3H,5H)-trithione
- Details on test material:
- Trithiocyanuric acid (TMT-H3)
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- New Zealand White
- Sex:
- male
Administration / exposure
- Type of coverage:
- not specified
- Vehicle:
- unchanged (no vehicle)
- Doses:
- 10.0 g/kg
- No. of animals per sex per dose:
- 5
- Control animals:
- no
Results and discussion
Effect levels
- Sex:
- male
- Dose descriptor:
- LD50
- Remarks on result:
- not determinable due to absence of adverse toxic effects
- Mortality:
- died/dosed: 0/5
- Clinical signs:
- other: no signs of intoxication and no skin irritation noted
- Gross pathology:
- no gross pathology noted
Any other information on results incl. tables
mean bw, i: 2.69
mean bw, t: 2.94
Applicant's summary and conclusion
- Interpretation of results:
- study cannot be used for classification
- Conclusions:
- LD 50 estimated at greater than 10.0 g/kg.
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