Registration Dossier
Registration Dossier
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EC number: 218-657-9 | CAS number: 2212-10-4
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
A 48-hour EC50 of > 100 mg/l was determined according to OECD 202 with the read accross substance (chloromethyl)trimethoxysilane CAS RN 5926-26-1.
Key value for chemical safety assessment
Additional information
Valid short term measured data are not available for (chloromethyl)diethoxymethylsilane (CAS No. 2212-10-4) therefore read across from the comparable substances, trimethoxy(methyl)silane (CAS No. 5926-26-1) was used to fill the data gap for invertebrates. A 48-hour EC50value of >100 mg/l and NOEC of ≥100 mg/l have been determined for the effects of the test substance on mobility of Daphnia magna based on nominal concentration of the substance. The study was conducted according to a standard guideline OECD 202 (Acute Toxicity forDaphnia) and GLP and was selected as raed accross study. However, it is likely that the test organisms were primarily exposed to the hydrolysis products of the substance.
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