Potassium benzoate

Stability in organic solvents and identity of relevant degradation products

Administrative data

Endpoint:

stability in organic solvents and identity of relevant degradation products

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because the stability of the substance is not considered to be critical

Justification for type of information:

The substance is poorly soluble in non-polar solvents. Benzoates are not dangerously reactive in oranic solvents.

Cross-reference

Cross-reference 1

Reason / purpose for cross-reference:

data waiving: supporting information

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

test procedure in accordance with generally accepted scientific standards and described in sufficient detail

Justification for type of information:

Screening assessment to confirm very high water solublity
At this level of solubility, accurate assessment is not necessary

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Version / remarks:

Screening study

GLP compliance:

no

Type of method:

flask method

Specific details on test material used for the study:

Batch no. SQU196
Appearance Prill
Composition Potassium benzoate > 99%

Key result

Water solubility:

ca. 492 g/L

Conc. based on:

test mat.

Loading of aqueous phase:

500 g/L

Incubation duration:

ca. 24 h

Temp.:

20 °C

pH:

ca. 9.2

Details on results:

Preliminary test, water solubility: 200-1000 g/l
Sample 1, 24 h: water solubility = 419.39 g/l, pH = 9.25
Sample 2, 48 h: water solubility = 493.85 g/l, pH = 9.22
Sample 3, 72 h: water solubility = 490.33 g/l, pH = 9.11
Values 2-3 are used for the calculation of the average of values.

Conclusions:

Very soluble in water.

Cross-reference 2

Reason / purpose for cross-reference:

data waiving: supporting information

Reference

Endpoint:

biodegradation in water: simulation testing on ultimate degradation in surface water

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because the substance is readily biodegradable

Justification for type of information:

A good level of biodegradation is noted with both benzoic acid and the sodium salt.  The absence of significant inhibition of microbial activity by potassium suggests that the potassium will not prevent biodegradation of benzoate and no accumulation in the environment is expected.
Potassium occurs naturally at high levels in soil and surface water.

Reason / purpose for cross-reference:

data waiving: supporting information