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Short-term toxicity to aquatic invertebrates

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Description of key information

The substance is acutely toxic to aquatic invertebrates.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
4.57 mg/L

Additional information

In the key study (NITE Japan, 2002; NMMP/E00/2090), the acute toxicity of 2,2'-dimethyl-4,4'-methylenebis(cyclohexylamine) (CAS 6864 -37 -5) was analyzed in a static test according to the OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test). The test item concentrations were analytically verified to be stable regarding sufficient recovery (> 80%).The 48-h EC50 was determined to be 4.57 mg/L (result based on not pH-adjusted test solutions).

In a supporting study (BASF AG, 1988; 1/0330/2/88-0330/88) according to EU Method C.2, Directive 79/831/EEC, Annex V, Part C, the 48-EC50 was determined to be 15.2 mg/L. Analytical monitoring of the test solutions was not conducted in this study.

In conclusion, the test substance is considered to be acutely toxic to aquatic invertebrates.