Registration Dossier
Registration Dossier
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EC number: 229-962-1 | CAS number: 6864-37-5
Acute Toxicity: other routes
Administrative data
- Endpoint:
- acute toxicity: other routes
- Type of information:
- experimental study
- Adequacy of study:
- disregarded due to major methodological deficiencies
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- other: Documentation insufficient for assessment, does not meet important criteria of today standard methods
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 959
- Report date:
- 1959
Materials and methods
- Principles of method if other than guideline:
- BASF-Test, see details in remarks on material and methods
- GLP compliance:
- no
- Remarks:
- pre GLP-study
Test material
- Reference substance name:
- 2,2'-dimethyl-4,4'-methylenebis(cyclohexylamine)
- EC Number:
- 229-962-1
- EC Name:
- 2,2'-dimethyl-4,4'-methylenebis(cyclohexylamine)
- Cas Number:
- 6864-37-5
- Molecular formula:
- C15H30N2
- IUPAC Name:
- 4-[(4-amino-3-methylcyclohexyl)methyl]-2-methylcyclohexan-1-amine
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- intraperitoneal
- Vehicle:
- other: Lutrol
- Doses:
- no data
- No. of animals per sex per dose:
- 21 animals (no gender stated)
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- ca. 47 mg/kg bw
- Remarks on result:
- other: original value: 50 µl/kg bw (conversion into mg/kg bw is based on the density d=0.94 g/cm3)
- Mortality:
- no data
- Clinical signs:
- no data
- Body weight:
- no data
- Gross pathology:
- no data
Applicant's summary and conclusion
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