Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 306-082-7 | CAS number: 95912-86-0
Sensitisation data (human)
Administrative data
- Endpoint:
- sensitisation data (humans)
- Type of information:
- experimental study
- Adequacy of study:
- disregarded due to major methodological deficiencies
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Only short abstract available. The analytical purity of the test substance was not specified, the available documentation is limited, the test substance concentration is not specified.
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 1 968
- Report date:
- 1968
Materials and methods
- Principles of method if other than guideline:
- 20 volunteers were exposed to the test substance in a sensitisation study, using a modified version of the test described by Schneider (Tübingen, Germany). The induction was performed by applying the test substance daily for 14 consecutive days. The challenge was performed folllowing a 14-day recovery period.
- GLP compliance:
- no
Test material
- Reference substance name:
- Fatty acids, C8-10, C12-18-alkyl esters
- EC Number:
- 306-082-7
- EC Name:
- Fatty acids, C8-10, C12-18-alkyl esters
- Cas Number:
- 95912-86-0
- Molecular formula:
- Unspecified
- IUPAC Name:
- Fatty acids, C8-10, C12-18 (even numbered)-alkyl esters
- Details on test material:
- - Name of test material (as cited in study report): only trade name given
- Analytical purity: no data
Constituent 1
Method
- Type of population:
- general
- Ethical approval:
- not specified
- Subjects:
- - Number of subjects exposed: 20
- Controls:
- No data
- Route of administration:
- dermal
- Details on study design:
- TYPE OF TEST(S) USED: patch test (epicutaneous test)
ADMINISTRATION
- Other: the induction was performed by applying the test substance daily for 14 consecutive days. The challenge was performed 14 days later.
Results and discussion
- Results of examinations:
- OTHER RESULTS:
No sensitizing effect was observed following the challenge exposure.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
