Registration Dossier
Registration Dossier
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EC number: 482-100-8 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Additional information
Earthworm
A key study was performed in accordance with OECD Guideline No. 207 to assess the acute toxicity of the test item to the earthworm (Eisenia foetida) in an artificial soil.
Following a preliminary range-finding test, 60 earthworms (six replicates of 10 worms) were exposed to a single concentration of 1,000 mg/kg of soil for a period of 14 days at a temperature of 20 to 23 degrees C. The number of mortalities were determined after 7 and 14 days exposure. A positive control using chloroacetamide, conducted approximately every 6 months, was reported for reference purposes.
The 14-day LC50 based on nominal test concentrations was greater than 1,000 mg/kg. The No Observed Effect Concentration was 1,000 mg/kg. The result of the positive control gave a 14-day LC50 for chloroacetamide of 32 mg/kg with 95% confidence limits of 29 to 35 mg/kg. The No Observed Effect Concentration was 18 mg/kg.
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