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Diss Factsheets

Ecotoxicological information

Toxicity to soil macroorganisms except arthropods

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Administrative data

Link to relevant study record(s)

Description of key information

The acute toxicity of the test item to the earthworm Eisenia foetida in an artificial soil test has been investigated and gave a 14-day LC50 value of greater than 1,000 mg/kg.  Correspondingly the No Observed Effect Concentration was 1,000 mg/kg.

Key value for chemical safety assessment

Short-term EC50 or LC50 for soil macroorganisms:
1 000 mg/kg soil dw

Additional information

A key study was performed in accordance with OECD Guideline No. 207 to assess the acute toxicity of the test item to the earthworm (Eisenia foetida) in an artificial soil. 

Following a preliminary range-finding test, 60 earthworms (six replicates of 10 worms) were exposed to a single concentration of 1,000 mg/kg of soil for a period of 14 days at a temperature of 20 to 23 degrees C. The number of mortalities were determined after 7 and 14 days exposure. A positive control using chloroacetamide, conducted approximately every 6 months, was reported for reference purposes.

The 14-day LC50 based on nominal test concentrations was greater than 1,000 mg/kg. The No Observed Effect Concentration was 1,000 mg/kg. The result of the positive control gave a 14-day LC50 for chloroacetamide of 32 mg/kg with 95% confidence limits of 29 to 35 mg/kg. The No Observed Effect Concentration was 18 mg/kg.