Registration Dossier
Registration Dossier
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EC number: 482-100-8 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Additional information
Hydrolysis
No experimental determination of the hydrolysis half-lide of the test material could be made due to the limitations of the test methods for a UVCB test material with low water solubility (< 0.26 mg/L) and where no suitable recovery methods or analysis were available. An estimate of hydrolytic stability using specialist chemical estimation software, HYDROWIN version 1.67, © 2000 U.S. Environmental Protection Agency, predicted the half-life to be 15.8 days at pH 8 and 158 days at pH 7. Furthermore, the substance is readily biodegradable.
Biodegradation
The test material attained 78% biodegradation after 28 days, but did not achieve >60% within the 10-day window. The test material may be considered as readily biodegradable as evidence of >70% degradation was attained over 28 days.
In an inherent biodegradation study, 31.5% degradation was measured in activated sludge within the 28 -day test period. This exceeded the % biodegradation pass level of 20%.
The test substance is considered readily and inherently biodegradable
Adsorption/desorption
The study was performed to OECD Guideline 121 and EC Method C.19 using the HPLC screening method.
The test item had no dissociation constants within the environmentally relevant pH range and therefore was tested in an unadjusted mobile phase. The sample was prepared in methanol.
The adsorption coefficient (Koc) of the test item has been determined to be > 4.27E05, Log Koc > 5.63.
Bioaccumulation
In accordance with Annex IX column 2 of the REACH Regulation, a study for bioaccumulation does not need to be conducted if the substance has a low potential for bioaccumulation. The experimentally derived Log Pow value for the substance has been identified as > 9.4. ECHA Guidance on Information requirements and chemical safety assessment Chapter R11: PBT assessment (page 28) on determination of bioaccumulation potential states: at very high log Kow (>6), a decreasing relationship between BCF and Log Pow is observed. Apart from experimental errors in the determination of BCF values for these very hydrophobic chemicals, reduced uptake due to the increasing molecular size may play a role as well. Moreover, the experimental determination of log Kow for very hydrophobic chemicals is normally also very uncertain due to experimental difficulties. Ideally the results of several model predictions should be considered. QSAR calculations of BCF for the components determined that the BCF < 500 L/kg. Therefore the substance is not considered to bioaccumulate.
Henry's Law Constant
Henry's law constant was calculated to be less than or equal to 3.81E03 Pa.m3/mol at 25 °C.
Environmental distribution
The substance is predicted to partition mainly to soil (ca.73%)
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