Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
hydrolysis
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1996
Report date:
1996

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: 92/69/EEC, C7
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
2,2,4-trimethyl-4-phenyl-butane-nitrile
EC Number:
422-580-8
EC Name:
2,2,4-trimethyl-4-phenyl-butane-nitrile
Cas Number:
75490-39-0
Molecular formula:
C13 H17 N
IUPAC Name:
2,2-dimethyl-4-phenylpentanenitrile

Results and discussion

Preliminary study:
Comments: Under the preliminary test conditions, Khusinil was found to undergo marginal hydrolysis at pH 7 (12%), moderate hydrolysis at pH 9 (19%), but no significant hydrolysis at pH 4, after 5 days at 50 deg C. Under test 1 conditions, Khusinil was found to undergo a pseudo first order reaction, therefore, test 3 was carried out at 60 and 70 deg C at pH 7 and pH 9.  The results indicate that the half-life times at 25 deg C are greater than one year at pH 7 and between one day and one year at pH 9.
Transformation products:
not measured

Applicant's summary and conclusion