Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1996
Report date:
1996

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: 92/69/EEC, C1
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
2,2,4-trimethyl-4-phenyl-butane-nitrile
EC Number:
422-580-8
EC Name:
2,2,4-trimethyl-4-phenyl-butane-nitrile
Cas Number:
75490-39-0
Molecular formula:
C13 H17 N
IUPAC Name:
2,2-dimethyl-4-phenylpentanenitrile

Test solutions

Details on test solutions:
Identity and concentration of auxiliary solvent for dispersal: The test substance was dispersed directly in test water, by
stirring for two hours, to give a series of stock solutions.

Test organisms

Test organisms (species):
Oncorhynchus mykiss (previous name: Salmo gairdneri)

Study design

Test type:
static

Test conditions

Hardness:
159 mg CaCO3/L

Results and discussion

Effect concentrationsopen allclose all
Duration:
24 h
Dose descriptor:
LC50
Effect conc.:
4.6 mg/L
Basis for effect:
mortality (fish)
Duration:
48 h
Dose descriptor:
LC50
Effect conc.:
4.6 mg/L
Basis for effect:
mortality (fish)
Duration:
72 h
Dose descriptor:
LC50
Effect conc.:
4.6 mg/L
Basis for effect:
mortality (fish)
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
4.6 mg/L
Basis for effect:
mortality (fish)
Duration:
96 h
Dose descriptor:
LC100
Effect conc.:
> 8.4 mg/L
Basis for effect:
mortality (fish)
Duration:
96 h
Dose descriptor:
NOEC
Effect conc.:
< 0.86 mg/L
Details on results:
%Concentration loss over test: 0 ... 60

Applicant's summary and conclusion