Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 273-521-6 | CAS number: 68988-22-7 A complex residuum from the distillation of products from the manufacture of dimethyl terephthalate by air oxidation and esterification of p-xylene. It consists of polyphenyl polyesters.
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 32 µg/L
- Assessment factor:
- 1 000
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 320 µg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 3.2 µg/L
- Assessment factor:
- 10 000
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 10 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 1.29 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 0.13 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 0.24 mg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Additional information
The following effect data are available for the submission substance:
1) Short term toxicity test on Cyprinus carpio:
NOEC = 100 mg/L (nominal concentration)
LC50 > 100 mg/L (nominal concentration)
2) Acute toxicity test on Daphnia magna:
NOEC (48h): 32 mg/L (nominal concentration)
EC50 (48h): 32 -56 mg/L (nominal concentration)
3) Toxicity test on freshwater algae (Pseudokirchnerella subcapitata)
Growth rate reduction (72h):
NOEC = 3.2 mg/L (nominal concentration)
EC50 >100 mg/L (nominal concentraion)
4) Toxicity to microorganisms (activated sludge respiration inhibition)
EC50 (3h) >100 mg/L (nominal concentration)
In the studies on aquatic toxicity only a small fraction of the loading rate was dissolved. As shown by measured TOC values test substance concentrations increased with increasing loading rates and were stable throughout the test. From this it can be concluded that only a small fraction (the "more water soluble fraction") of this UVCB substance is solved in water and that its concentration in water is depending on the total amount of substance provided to the water phase. As it is reasonable to assume that this solved fraction is available to aquatic organisms and is responsible for the aquatic toxicity observed, the nominal concentrations (loading rates) are used to characterise the observed toxicity.
The most sensitve endpoint is therfore acute toxicity to Daphnia magna with an EC50 (48h) of 32 - 56 mg/L (nominal concentration). Some effects are seen on algal growth rate. For fish and microorganisms, no effects could be observed at the applied limit concentration of 100 mg/L nominal. Therefore, PNECs were derived based on the effect value obtained for Daphnia magna.
According to the REACH guidance on information requirements and chemical safety assessment part R.7A, "substances with a Koc below 500 -1000 L/kg are generally unlikely to adsorb zu sediment". As the Koc-value (calculated) determined as result of a weight of evidence approach for the UVCB submission substance is 366.4 L/kg, partitioning to sediment and soil is most probably of minor importance. The derived PNECs for sediment and soil wet weight (34.1 and 25.7 µg/kg, respectively) are about one order of magnitude higher than the PNECaqua.
Conclusion on classification
The most sensitive endpoint for the submission substance is acute toxicity to Daphnia magna with an EC50 (48h) of 32 - 56 mg/L (nominal concentration). The submission substance is not readily biodegradable (26.5% biodegradation as average of duplicate samples within 28 days).
Therefore, the submission substance is classified according to Regulation 1272/2008 EC as
Hazardous to the aquatic environment: Chronic Category 3 (H412)
Therefore, the submission substance is classified according to directive 67/548 EC with R52/R53
Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.