Registration Dossier
Registration Dossier
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EC number: 273-521-6 | CAS number: 68988-22-7 A complex residuum from the distillation of products from the manufacture of dimethyl terephthalate by air oxidation and esterification of p-xylene. It consists of polyphenyl polyesters.
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Invertebrate toxicity of the submission substance was determined on Daphnia magna according to OECD 202 and EU-method C.2:
EC50 (48h): 32 -56 mg/L (nominal concentration).
Key value for chemical safety assessment
Additional information
The submission substance was tested for acute toxicity on invertebrates by an acute toxicity test on Daphnia magna according to OECD 202 and EU-method C.2 (GLP-compliance). As the test item was not fully soluble in water, measured concentrations are deviating significiantly from the nominal concentrations. As shown by measured TOC values test substance concentrations increased with increasing loading rates and were stable throughout the test. From this it can be concluded that only a small fraction (the "more water soluble fraction") of this UVCB substance is solved in water and that its concentration in water is depending on the total amount of substance provided to the water phase. As it is reasonable to assume that this solved fraction is available to aquatic organisms and is responsible for the aquatic toxicity observed, the nominal concentrations (loading rate) are used to characterise the observed toxicity.
Effect concentrations:
NOEC (48h): 2.9 mg/L measured (32 mg/L nominal)
EC50 (48h): 3.9 mg/L measured (95% CI 2.9-5.2 mg/l);
EC50 (48h): 32 -56 mg/L nominal concentration;
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