Registration Dossier
Registration Dossier
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EC number: 800-353-8 | CAS number: 1379524-06-7
Partition coefficient
Administrative data
Link to relevant study record(s)
Description of key information
The Log Kow (Pow) of Amides, C18-unsatd., N-[3-(dimethylamine)propyl] was determined to be 6.1 for the C18:1 carbon chain component, 5.3 for the C18:2 carbon chain component and 4.6 for the C18:3 carbon chain component.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 6.1
- at the temperature of:
- 25 °C
Additional information
A partition coefficient 1-octanol/water test for Amides, C18-unsatd., N-[3-(dimethylamine)propyl] has been performed according to OECD guideline for testing of chemicals, No. 123. The test substance consisted of several components of which the C18 carbon chain components with one, two and three double bonds represent the main components. These components were analyzed for calculating the Pow results.
A summary of the results is presented below.
C18’-component
Average 6.1
C18’’-component
Average 5.3
C18’’’-component
Average 4.6
In the Chapter R.7A of the REACH guidance (Section R.7.1.8.3; Guidance on regulatory compliant Kow determination for surfactants), it is indicated that none of the experimental methods is very well suited for determining the Kow of surface active chemicals. The slow stirring method seems to be the best in theory, but still not demonstrated to be perfect. Indeed, due to the physico-chemical properties of surfactants, specifically their tendency to either accumulate at the octanol/water interface or to coat the surfaces of the above-described HPLC adsorbent phase, the logKow of surfactants cannot be accurately measured for these substances. Therefore, the log Kow values of Amides, rape-oil, N-[3-(dimethylamino)propyl]
can not be used to predict the partitioning behaviour (sorption or bioaccumulation potential) of this compound.Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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