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Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Key value for chemical safety assessment

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To address the bioaccumulation potential according to REACH requirements, the log Kow of Amides, C18-unsatd., N-[3-(dimethylamine)propyl] was measured applying slow stirring method according to OECD 123. The observed log Kow value (Log Kow>3) indicates that the substance may have a bioaccumulation potential if Amides, C18-unsatd., N-[3-(dimethylamine)propyl] would have been a narcotic substance. For polar narcotics like Amides, C18-unsatd., N-[3-(dimethylamine)propyl] however there is only limited information on the relationship between log Kow and BCF. Performance of a standard aquatic exposure based OECD 305 test is however not considered. Amides, C18-unsatd., N-[3-(dimethylamine)propyl] sorbs easily to negatively charged surfaces like glassware, clay etc... Standard OECD 305 tests are therefore technically not feasible with these strongly sorbing easily degradable substances. In addition is the route of exposure unrealistic for these substances because the substance will either be sorbed or biodegraded.