Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 214-029-3 | CAS number: 1073-69-4
Eye irritation
Administrative data
- Endpoint:
- eye irritation: in vivo
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Only limited documentation
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Toxicity of phenylhydrazine in inhalatory exposure
- Author:
- Pham KC
- Year:
- 1 979
- Bibliographic source:
- Gigiena Truda i Professional'nye Zabolevaniya, 3:45-47; cited in WHO 2000, Phenylhydrazine. CICAD 19, Wissenschaftliche Verlagsgesellschaft mbH, Stuttgart, ISBN 92 4 153019 7; ISSN 1020-6167.
- Reference Type:
- publication
- Title:
- Toxicity of phenylhydrazine in inhalatory exposure
- Author:
- Pham KC
- Year:
- 1 979
- Bibliographic source:
- Gigiena Truda i Professional'nye Zabolevaniya, 3:45-47; cited in BUA (1995) Phenylhydrazine. Stuttgart, S. Hirzel, Wissenschaftliche Verlagsgesellschaft (Report No. 120; ISBN 3-7776-0691-X).
- Reference Type:
- secondary source
- Title:
- Concise International Assessment Document 19: Phenylhydrazine
- Author:
- WHO
- Year:
- 2 000
- Bibliographic source:
- Wissenschaftliche Verlagsgesellschaft mbH, Stuttgart, ISBN 92 4 153019 7; ISSN 1020-6167
- Reference Type:
- secondary source
- Title:
- Unnamed
- Year:
- 1 994
Materials and methods
- Principles of method if other than guideline:
- 50 % solution of phenylhydrazine is applicated to the eyes of rabbits.
- GLP compliance:
- no
Test material
Reference
- Name:
- Unnamed
- Type:
- Constituent
- Details on test material:
- no data
Test animals / tissue source
- Species:
- rabbit
- Strain:
- not specified
- Details on test animals or tissues and environmental conditions:
- no data
Test system
- Vehicle:
- not specified
- Controls:
- not specified
- Amount / concentration applied:
- TEST MATERIAL
- Concentration (if solution): 50 % - Duration of treatment / exposure:
- no data
- Observation period (in vivo):
- no data
- Number of animals or in vitro replicates:
- no data
- Details on study design:
- no data
Results and discussion
In vivo
Results
- Irritation parameter:
- other: Irritation
- Basis:
- other: no data
- Time point:
- other: no data
- Score:
- > 0
- Reversibility:
- not specified
- Remarks on result:
- other: The available data clearly indicates that the test substance is irritating to the eye although no scores have been provided.
- Irritant / corrosive response data:
- see remarks on results
- Other effects:
- no data
Any other information on results incl. tables
Applicant's summary and conclusion
- Interpretation of results:
- Category 2A (irritating to eyes) based on GHS criteria
- Remarks:
- Migrated information
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