Registration Dossier
Registration Dossier
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EC number: 610-200-5 | CAS number: 446292-07-5
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
No antigen specific activation of the cells of the immune system via dermal route was determined after application of up to and including 30% Hydroxyaminophthalimid. No indication for a non-specific (irritating) activation was detected, too. Therefore, the study does neither point to a non-specific (irritating) nor to a specific immunostimulating (sensitising) potential of the test item.
Migrated from Short description of key information:
Skin Sensitisation, LLNA/IMDS (NMRI mice, GLP, OECD TG 429, 406 and EPA OPPTS 870.2600): no non-specific (irritating) or specific immunostimulating (sensitising) properties
[Bayer AG, Report No. PH-34740, 2007-01-18]
Justification for classification or non-classification
Based on the study results a classification according to Directive 67/548/EEC and Regulation (EC) No. 1272/2008 (CLP) is not required.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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