Registration Dossier
Registration Dossier
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EC number: 464-520-3 | CAS number: 189813-45-4
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 006
- Report date:
- 2006
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 A (Ready Biodegradability: DOC Die Away Test)
- GLP compliance:
- yes
Test material
Reference
- Name:
- Unnamed
- Type:
- Constituent
- Details on test material:
- - Name of test material (as cited in study report): 520 F - Chlormethyloximether
- Physical state: solid/ dark green
- Analytical purity: 94.4 g/100 g
- Batch No.: 31196-182
- Storage condition of test material: room temperature
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge: municipal activated sludge from the wastewater treatment plant
- Preparation of inoculum for exposure: An appropriate aliquot of the activated sludge suspension was sieved with a finely woven mesh (mesh size about 1 mm), washed with tap water, and pre-aerated for about 24 hours. The sludge of this suspension was adjusted to a concentration of 6.0 g/L of dry weight and then added to the test vessels to obtain a sludge concentration of 30 mg/L dry substance. - Duration of test (contact time):
- 28 d
Initial test substance concentrationopen allclose all
- Initial conc.:
- 37 mg/L
- Based on:
- test mat.
- Initial conc.:
- 20 mg/L
- Based on:
- DOC
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- DOC removal
- Details on study design:
- TEST CONDITIONS
- Composition of medium per vessel (total volume = 1000 ml): 106 ml (37 mg/L) test substance, 5 ml (30 mg/L dry matter) inoculum, 876 ml deionized water, 13 ml inorganic medium
SAMPLING
- Sampling frequency: after 0, 1, 3, 5, 7, 10, 14, 17, 21, 24, 27 and 28 days
CONTROL AND BLANK SYSTEM
- Blank control: 2 replicates
- Abiotic sterile control: 1 replicate
- Inhibition control: 1 replicate
- Adsorption control: 1 replicate
- Reference substance: 1 replicate
- Test substance: 2 replicates
Results and discussion
% Degradation
- Parameter:
- % degradation (DOC removal)
- Value:
- 10 - 20
- Sampling time:
- 28 d
- Details on results:
- Degradation kinetic:
3% after 1 day
12% after 3 days
12% after 17 days
17% after 28 days
Applicant's summary and conclusion
- Interpretation of results:
- other: poorly biodegradable
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