Registration Dossier
Registration Dossier
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EC number: 435-860-1 | CAS number: 214417-91-1
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Two algal growth inhibition studies in Pseudokirchnerella subcapitata were performed in accordance with OECD 201 guideline and GLP principles.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 2.5 mg/L
- EC10 or NOEC for freshwater algae:
- 0.23 mg/L
Additional information
The EC50 for growth rate reduction (ERC50: 0 -72h) was 2.5 mg/l with a 95 % confidence interval ranging from 1.0 to 6.1 mg/l.
The EC10 for growth rate reduction (ERC10: 0-72h) was 0.23 mg/l with a 95 % confidence interval ranging from -0.71 to 1.2 mg/l.
The NOEC for growth rate reduction corresponded with an average exposure concentration of 0.08 mg/l.
The testsubstance concentration was not stable during the exposure period (because of hydrolysis). It is not possible to avoid degradation in an algae test as it is a static test and cannot be performed under semi-static or flow-through conditions. The reported endpoints should be interpreted as worst-case endpoints, i.e., all observed toxicity is attributed to the testsubstance (at its measured concentration) and not to the degradation products.
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