Di(tetraethylammonium)hexahydroxoplatinate(IV)

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

flask method

Specific details on test material used for the study:

SOURCE OF TEST MATERIAL
- Source and lot/batch number of test material: 3341/00-F9
- Expiration date of the lot/batch: August 06, 2020
- Purity test date: Certificate of analysis dated August 06, 2019

STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: Room temperature (10°C to 30 °C), dark, dry

FORM OF TEST MATERIAL
- Content: 10.94 % Pt
- Form: liquid
- Appearance: clear orange liquid

Water solubility:

> 1 000 g/L

Temp.:

22 °C

pH:

> 12

Preliminary test

A defined volume of demineralized water was added at room temperature to a defined amount of the test item. After the addition of water the mixture was visually checked for any undissolved particles.

Table1: Results of the preliminary test, part 1

Amount of test item / mg	Added volume of demineralized water / ml	Total volume of demineralized water / ml	Appearance of mixture
115.5	0.1	0.1	dissolved

The preliminary test showed that the water solubility of the test item was > 1000 g/l. For this reason an extended preliminary test was performed. It was investigated if the test item was miscible with demineralized water in different ratios.

Table2: Results of the preliminary test, part 2

Experiment	A	B	C
Amount of test item (ml)	0.5	2.5	4.5
Amount of demin. water (ml)	4.5	2.5	0.5
Ratio	1:9	1:1	9:1
Appearance of the mixtures	dissolved	dissolved	dissolved
pH value of the mixture	12.3	13.2	13.6

The test item was miscible with water at room temperature (T = 22 °C) in all tested ratios (1:1, 1:9, 9:1).

Flask method

The flask method was performed. As the test item is a mixture of different components experiments with two loading rates were performed as recommend in the ECHA guidance R.7a. The data for the evaluation are given in Table3. After the equilibration time one liquid phase was observed in the flasks of the experiments excluding in the blank experiment. For details see Table3.

Table3: Water solubility experiments of the test item, loading rate 500 g/l

Experiment	24 h experiment	48 h experiment	72 h experiment	Blank experiment (72 h)
Amount of test item / mg	20.0	20.1	20.0	--
Amount of demineralized water / ml	40	40	40	40
Stirring time at 30 °C / h	24	48	72	72
pH at ambient temperature at the start of the experiment	12.9	12.9	12.9	5.9
pH at ambient temperature at the end of the experiment	12.9	12.9	12.9	6.0
Appearance of the mixtures	dissolved	dissolved	dissolved	-
Water solubility / g/l	> 500	> 500	> 500	-

 

Table4: Water solubility experiments of the test item, loading rate 500 g/l

Experiment	24 h experiment	48 h experiment	72 h experiment	Blank experiment (72 h)
Amount of test item / mg	20.0	20.0	20.0	-
Amount of demineralized water / ml	20	20	20	-
Stirring time at 30 °C / h	24	48	72	-
pH at ambient temperature at the start of the experiment	13.2	13.2	13.2	-
pH at ambient temperature at the end of the experiment	13.1	13.1	13.0	-
Appearance of the mixtures	dissolved	dissolved	dissolved	-
Water solubility / g/l	> 1000	> 1000	> 1000	-

 

The water solubility of the test item at 20 °C was determined to be > 1000 g/l in the main test.

Conclusions:

The water solubility of the test item at 20 °C was determined to be > 1000 g/l.

Executive summary:

Winkler (2020) is a GLP-compliant study following OECD guideline 105 and EU method A6. It is reliable without restrictions and can be used as a key study for this endpoint. The flask method was performed. The water solubility of the test item at 20 °C was determined to be > 1000 g/l.

Description of key information

The water solubility of the test item at 20 °C was determined to be > 1000 g/l.

Key value for chemical safety assessment

Water solubility:

1 000 g/L

at the temperature of:

20 °C

Additional information

Winkler (2020) is a GLP-compliant study following OECD guideline 105 and EU method A6. It is reliable without restrictions and can be used as a key study for this endpoint. The flask method was performed. The water solubility of the test item at 20 °C was determined to be > 1000 g/l.