Registration Dossier
Registration Dossier
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EC number: 701-314-7 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Skin Irritation – minimal irritation for rabbits (OECD 404).
Eye Irritation – minimal irritation for rabbits (OECD 405).
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
As assessed in dermal irritation studies, the registered substance is transiently irritating to the skin. In a study utilizing an occluded patch exposure, the presence of erythema was noted within 4 hours of patch removal and remained present until at least seven days post exposure. The severity of the erythema induced by the registered substance exposure ranged from very slight to severe during this time frame. However, upon removal, signs of irritation subside. The registered substance is also transiently irritating to the eye as assessed in rabbits. Redness was noted in all animals up to 24h post exposure and decreased steadily through 14 days post exposure.
Justification for classification or non-classification
No classification for irritation is indicated according to the general classification and labeling requirements for dangerous substances and preparations (Directive 67-548-EEC) or the classification, labeling and packaging (CLP) regulation (EC) No 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
