Registration Dossier
Registration Dossier
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EC number: 266-411-4 | CAS number: 66576-71-4
Basic toxicokinetics
Administrative data
- Endpoint:
- basic toxicokinetics, other
- Type of information:
- other: Literature review
- Study period:
- 1998 - 1999
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 1 998
- Report date:
- 1998
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 1 999
- Report date:
- 1999
Materials and methods
- Objective of study:
- absorption
- metabolism
Test guideline
- Qualifier:
- no guideline required
Test material
- Reference substance name:
- Isopropyl 2-methylbutyrate
- EC Number:
- 266-411-4
- EC Name:
- Isopropyl 2-methylbutyrate
- Cas Number:
- 66576-71-4
- Molecular formula:
- C8H16O2
- IUPAC Name:
- isopropyl 2-methylbutyrate
- Test material form:
- liquid
Constituent 1
- Radiolabelling:
- no
Test animals
- Species:
- other: none
Administration / exposure
- Route of administration:
- oral: feed
Results and discussion
Main ADME resultsopen allclose all
- Type:
- absorption
- Results:
- Short branched chain carboxylic acids and their esters are rapidly absorbed from the gastrointestinal tract.
- Type:
- metabolism
- Results:
- Hydrolysis of Isopropyl Methyl-2-Butyrate would be catalysed by esterases occurs in the gastrointestinal tract, skin, blood or liver forming ethanol and a carboxylic acid.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
