Registration Dossier
Registration Dossier
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EC number: 262-075-8 | CAS number: 60142-95-2
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2010
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 010
- Report date:
- 2010
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 1-(aminomethyl)cyclohexaneacetic acid hydrochloride
- EC Number:
- 262-075-8
- EC Name:
- 1-(aminomethyl)cyclohexaneacetic acid hydrochloride
- Cas Number:
- 60142-95-2
- Molecular formula:
- C9H17NO2.ClH
- IUPAC Name:
- 2-[1-(aminomethyl)cyclohexyl]acetic acid hydrochloride
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
Test solutions
- Vehicle:
- no
Test organisms
- Test organisms (species):
- Daphnia magna
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 48 h
Test conditions
- Test temperature:
- 18-22°C, +/-1°C constant
- pH:
- 7.8 +/- 0.2
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 48 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
Any other information on results incl. tables
| Test Duration [h] | Nominal Test Item Concentration [mg/L] |
Confidence Interval p=95% |
|
| EC 50 | 24 | > 100 | not applicable |
| 48 | > 100 | not applicable | |
| EC 100 | 24 | > 100 | -- |
| 48 | > 100 | -- | |
| NOEC | 48 | 100 | -- |
| LOEC | 48 | > 100 | -- |
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- At the limit concentration 100mg/L (nominal) of the test item Gabapentin HCl no effect was observed.
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