2,3,4-trihydroxybenzophenone

Melting point / freezing point

Link to relevant study record(s)

Reference

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2015-07-02 to 2015-07-20

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Reason / purpose for cross-reference:

reference to same study

Reason / purpose for cross-reference:

reference to same study

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

Version / remarks:

2008

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

Deviations:

no

GLP compliance:

no

Type of method:

differential scanning calorimetry

Key result

Melting / freezing pt.:

>= 141 - <= 143 °C

Remarks on result:

other:

Remarks:

Pressure not specified. Atmospheric pressure is presumed.

Three DSC measurements with a heating rate of 10 K/min showed an endothermal effect (melting) in the temperature range of 135-170 °C. The onset temperature (see Table 1) was derived from the intersection of the tangent line with the highest slope of the endothermal peak with the baseline. The results of the DSC measurements are summarized in Table 1.

 

Table 1: Melting point (DSC measurements)

Ident No.	Test item/mg	Starting temperature/ °C	Final test temperature / °C	Temperature range(melting)/ °C	Onset/ °C	Crucible	Observations
35138	7.35	25	500	135-160	141.1	Aluminium with a hole	-
35142	8.57	25	500	135-160	142.8	Aluminium with a hole	-
35150	10.08	25	200	135-155	141.8	Aluminium with a hole	Test item was a solidified melt after the measurement

 The test item had a melting range of 141 -143 °C.

Conclusions:

The DSC measurements (25 - 500 °C) showed that the test item had a melting range of 141 - 143 °C.

Executive summary:

A study was conducted according to OECD test guideline 102 and Regulation (EC) No 440/2008 method A.1. The melting range was determined by differential scanning calorimetry (DSC 25 - 500 °C). The test item and the reference were heated up from the starting temperature to the final temperature at a constant heating rate of 10 K/min in a defined atmosphere (nitrogen). Open crucibles were used as containers for the test item and as empty reference crucible. The quantity of heat absorbed or released was measured and recorded. The DSC measurements (25 - 500 °C) showed that the test item had a melting range of 141 - 143 °C. 

Description of key information

The DSC measurements (25 - 500 °C) showed that the test item had a melting range of 141 - 143 °C. 

Additional information

A study was conducted according to OECD test guideline 102 and Regulation (EC) No 440/2008 method A.1. The melting range was determined by differential scanning calorimetry (DSC 25 - 500 °C). The test item and the reference were heated up from the starting temperature to the final temperature at a constant heating rate of 10 K/min in a defined atmosphere (nitrogen). Open crucibles were used as containers for the test item and as empty reference crucible. The quantity of heat absorbed or released was measured and recorded. The DSC measurements (25 - 500 °C) showed that the test item had a melting range of 141 - 143 °C.