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EC number: 216-365-6 | CAS number: 1565-76-0
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 30-Mar-2015 to 01-Apr-2015
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 123 (Partition Coefficient (1-Octanol / Water), Slow-Stirring Method)
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- Staatliches Gewerbeaufsichtsamt Hildesheilm
- Type of method:
- slow-stirring method
- Partition coefficient type:
- octanol-water
- Key result
- Type:
- log Pow
- Partition coefficient:
- 4.369
- Temp.:
- 25 °C
- pH:
- 5.53
- Conclusions:
- A log Pow value of 4.369 (at 25 °C) was determined for the test substance according to OECD Guideline 123.
Reference
Results
Table of results
Replicate number |
Test duration (h) |
Measured concentration |
Pow |
Log Pow |
||||
in n-octanol (mg/L) |
in Aq. phase (mg/L) |
Single |
Mean |
SD +/- |
CV |
|||
1 |
41.83 |
16720 |
0.810 |
20642 |
4.31 |
4.35 |
0.03 |
0.68 |
46.83 |
16925 |
0.785 |
21561 |
4.33 |
||||
66.08 |
16590 |
0.686 |
24201 |
4.38 |
||||
71.08 |
16540 |
0.737 |
22458 |
4.35 |
||||
2 |
41.83 |
16575 |
0.698 |
23763 |
4.38 |
4.38 |
0.01 |
0.24 |
46.83 |
16505 |
0.708 |
23329 |
4.37 |
||||
66.08 |
16390 |
0.664 |
24684 |
4.39 |
||||
71.08 |
16030 |
0.676 |
23713 |
4.37 |
||||
3
|
41.83 |
16710 |
0.700 |
23871 |
4.38 |
4.36 |
0.01 |
0.29 |
46.83 |
16325 |
0.720 |
22674 |
4.36 |
||||
66.08 |
16450 |
0.728 |
22596 |
4.35 |
||||
|
71.08 |
16530 |
0.739 |
22383 |
4.35 |
|||
Log Pow, Av = 4.369
σ Log Pow, Av = 0.012
aq. phase = Aqueous phase
Pow = Partition coefficient (n-octanol / water)
Log Pow = Decadic logarithm of the partition coefficient (n-octanol / water)
SD = Standard Deviation
CV = Coefficient of variation (%)
Log Pow, Av = Weighted average value of log Pow
σLog Pow, Av = Weighted standard deviation
Conclusions
The partition coefficient (n-octanol/water) (log Pow) of the test substance was determined at a test temperature of 25 ±1 °C and at a pH value of 5.532 from three independent replicates (test vessels) with four sub-replicates (samples) to be 4.369 ±0.012.
Description of key information
Log Pow: 4.369 at 25 °C (OECD Guideline 123, slow stirring)
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 4.369
- at the temperature of:
- 25 °C
Additional information
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