Registration Dossier
Registration Dossier
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EC number: 920-338-0 | CAS number: 109236-76-2
Solubility in organic solvents / fat solubility
Administrative data
- Endpoint:
- solubility in organic solvents / fat solubility
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
Cross-reference
- Reason / purpose for cross-reference:
- reference to same study
Reference
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- column elution method
- Key result
- Water solubility:
- < 4 ppb
- Conc. based on:
- test mat.
- Temp.:
- 23 °C
- pH:
- >= 6.11 - <= 6.33
- Conclusions:
- The solubility of the test item is below the LOQ of the analytical method (< 4 ppb). This supports the result of the solubilty tests in the aquatic toxicity test.
Data source
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Guideline:
- OECD Guideline 116 (Fat Solubility of Solid and Liquid Substances)
- Principles of method if other than guideline:
- The solubility in organic solvents was measured in the study of water solubility in order to elaborate the analytical method. The test was made as a kind of limit test with qualitative observation.
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- Gawarol
- IUPAC Name:
- Gawarol
- Test material form:
- solid: crystalline
Constituent 1
Results and discussion
Solubility in organic solvents / fat solubilityopen allclose all
- Medium:
- n-octanol
- Solubility:
- >= 1.7 g/L
- Temp.:
- 20 °C
- Medium:
- acetone
- Solubility:
- >= 1.18 g/L
- Temp.:
- 20 °C
- Medium:
- isopropanol
- Solubility:
- >= 1.25 g/L
- Temp.:
- 20 °C
- Medium:
- acetonitrile
- Solubility:
- < 1.2 g/L
- Temp.:
- 20 °C
- Medium:
- methanol
- Solubility:
- < 1.1 g/L
- Test substance stable:
- yes
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
