Registration Dossier
Registration Dossier
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EC number: 241-893-9 | CAS number: 17976-32-8
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
The mutagenic potential of the analogue was evaluated in a Salmonella/microsome test with the S. typhimurium strains TA 98, TA 100, TA 102, TA 1535 and TA 1537 in the presence and absence of S9 mix according to OECD TG 471. Evidence of mutagenic activity was not seen up to the maximum recommended dose level of 5000 µg/plate. No substantial increases in revertant colony numbers of any of the five tester strains were observed at any dose level in the presence and absence of metabolic activation. There was also no tendency of higher mutation rates with increasing concentrations in the range below the generally acknowledged border of biological relevance. Therefore, the analogue was considered to be non-mutagenic in the Salmonella typhimurium reverse mutation assay.
Endpoint Conclusion:
Justification for classification or non-classification
Based on the study results of the analogue a classification according to Directive 67/548/EEC or Regulation (EC) No. 1272/2008 (CLP) is not warranted.
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