Registration Dossier
Registration Dossier
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EC number: 400-820-2 | CAS number: 84268-33-7
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Guideline study obtained through inquiry process; SNIF file obtained from ECHA.
Data source
Reference
- Reference Type:
- other: SNIF
- Title:
- Unnamed
- Year:
- 1 986
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- not specified
- GLP compliance:
- yes
Test material
- Reference substance name:
- Body responsible for the test
- IUPAC Name:
- Body responsible for the test
- Test material form:
- not specified
Constituent 1
Sampling and analysis
- Analytical monitoring:
- not specified
Test solutions
- Vehicle:
- yes
- Details on test solutions:
- The carrier solvent was tetrahydrofuran and Arkopal N150
Test organisms
- Test organisms (species):
- Daphnia magna
Study design
- Test type:
- not specified
- Water media type:
- freshwater
- Total exposure duration:
- 48 h
Test conditions
- Reference substance (positive control):
- not specified
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 66 mg/L
- Duration:
- 48 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 5.9 mg/L
- Details on results:
- The test substance precipitated immediately at 100 mg/L nominal concentration. A few individuals were immobilised by the precipitate sticking to them.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Conclusions:
- EC50 > 66 mg/L (48h)
NOEC = 5.9 mg/L (48h)
Due to its very low water solubility (see IUCLID section 4.8), the test substance is considered not to be toxic to aquatic invertebrates under the conditions of the test. - Executive summary:
The acute toxicity of the test substance to aquatic invertebrates has been determined in a test with Daphnia Magna according to OECD Guideline 202 . The EC50 was > 66 mg/L (48h) and the NOEC was 5.9 mg/L (48h). Hence, it can be stated that there is no toxicity in the range of the low water solubility of the test substance. Therefore, the test substance is considered not to be harmful to aquatic invertebrates.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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