Leach residues, zinc ore, lead-contg.

Short-term toxicity to fish

Link to relevant study record(s)

Reference

Endpoint:

short-term toxicity to fish

Type of information:

calculation (if not (Q)SAR)

Remarks:

Migrated phrase: estimated by calculation

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Automatic calculation with MeCLas Tool

Reason / purpose for cross-reference:

reference to same study

Reason / purpose for cross-reference:

reference to other study

Principles of method if other than guideline:

Aquatic toxicity of the UVCB substance was determined by classifying based on Mixture rules from EU CLP ( tier 1= summation of classified components or Tier 2 = additivity of soluble components to derive Hazard class) and back calculation to the corresponding L(E)C50 range

Duration:

96 h

Dose descriptor:

EC50

Effect conc.:

<= 1 mg/L

Nominal / measured:

estimated

Conc. based on:

test mat.

Basis for effect:

other: most sensitive species

Sublethal observations / clinical signs:

According to MeClas, the substance is classified as acute 1 to environment.

Validity criteria fulfilled:

yes

Conclusions:

Good quality estimate of the L/EC50 of the UVCB substance.
The substance is classified as acute cat 1 to environment resulting in a L(E)C50 < 1 mg/L.

Executive summary:

The study provided a conservative estimate of the effect concentration, derived on basis of the classification outcome (mixture toxicity rules) from a reasonable worst-case sample of the substance using mineralogical information from the representative sample. 

 

Validity of the model used:

1. Defined endpoint: the endpoint is a REACH compliant defined endpoint

2. Unambiguous algorithm: EU CLP guidance based summation formula to determine classification, followed by back-calculation to related hazard criteria

3. Applicability domain: applicable to classify complex metal containing materials. 

4. Mechanistic interpretation - metal species: the tool translates the elemental composition into a mineralogical composition relevant for classification.

 

Description of key information

No PNEC derived for the UVCB itself.

Short-term toxicity to fish is driven by the characteristics of the individual UVCB constituents. Relevant information on the individual UVCB constituents is reported in IUCLID Section 6 Summary. Individual UVCB constituents-specific information is used for classification and risk assessment.