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EC number: 308-760-8 | CAS number: 98246-87-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- disregarded due to major methodological deficiencies
- Study period:
- 1975
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- The study was performed before OECD test guidelines and GLP were established. The documentation is according to the best practice at the time the study was performed. However, some critical details of the test protocol and the results are not available. This study is not comparable with an acute inhalation toxicity study according to OECD test guideline no. 403. The study determined the effects of inhaling a saturated atmosphere at room temperature. Since the vapour pressure of the test substance is extremely low, there was virtually no exposure.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 976
- Report date:
- 1976
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- BASF Inhalation Hazard Test
- GLP compliance:
- no
- Remarks:
- Pre-GLP
- Limit test:
- yes
Test material
- Reference substance name:
- 2-Oxetanone, 3-C14-16-alkyl 4-C15-17-alkylidene derivs.
- EC Number:
- 308-760-8
- EC Name:
- 2-Oxetanone, 3-C14-16-alkyl 4-C15-17-alkylidene derivs.
- Cas Number:
- 98246-87-8
- Molecular formula:
- C32H60O2 / C34H64O2 / C36H68O2
- IUPAC Name:
- 4-(C15-C17) alkylidene-3-(C14-16) alkyloxetan-2one
- Details on test material:
- Attached to the oxetane ring there is a C14 or C16 alkyl group in the 3-position and a C15 or C17 alkylidene group in the 4-position. The appropriate EC number for this substance is EC 308-760-8 (EC name: 2-Oxetanone, 3-C14-16-alkyl 4-C15-17-alkylidene derivs.)
Constituent 1
- Specific details on test material used for the study:
- Test substance: other TS: Stearyldiketen TV 194/37
An AKD manufactured using a stearic acid rich blend of palmitic and stearic fatty acids.
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- inhalation: vapour
- Type of inhalation exposure:
- not specified
- Vehicle:
- other: unchanged (no vehicle)
- Analytical verification of test atmosphere concentrations:
- no
- Duration of exposure:
- 8 h
- No. of animals per sex per dose:
- 12
Results and discussion
Effect levels
- Remarks on result:
- other: No mortality was observed when 12 rats were exposed for 8 hours to an atmosphere that has been saturated at 20 degrees celcius with the volatile part of the compound.
- Clinical signs:
- other:
Any other information on results incl. tables
Test Conditions: This test was performed according to principle described in OECD TG 403. It demonstrates the toxicity of an atmosphersaturated with
vapours of the volatile components of the test substance. Groups of three young adult rats were sequentially exposed to the vapours, generated by bubbling 200L/h air through a 5 cm column of the test substance. No analytical determination of the atmosphere concentration was performed.
However, very little AKD vapour is expected to be present in an atmosphere saturated with AKD vapour, since the vapour pressure of AKD is extremely low
with an estimated 3x10-6 hPa at 40o Celsius. The study allows for an estimate of the length of time required to cause severe toxicity by exposure to a
saturated atmosphere. The study does not allow any estimation of the inhalation toxicity of AKD dusts.
Applicant's summary and conclusion
- Interpretation of results:
- other: Due to limited reporting interpretation is not possible.
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