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EC number: 239-931-4 | CAS number: 15827-60-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Distribution modelling
Administrative data
- Endpoint:
- distribution modelling
- Type of information:
- calculation (if not (Q)SAR)
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- accepted calculation method
Data source
Materials and methods
- Model:
- calculation according to Mackay, Level III
- Media:
- air - biota - sediment(s) - soil - water
Test material
- Reference substance name:
- [[(phosphonomethyl)imino]bis[ethane-2,1-diylnitrilobis(methylene)]]tetrakisphosphonic acid
- EC Number:
- 239-931-4
- EC Name:
- [[(phosphonomethyl)imino]bis[ethane-2,1-diylnitrilobis(methylene)]]tetrakisphosphonic acid
- Cas Number:
- 15827-60-8
- Molecular formula:
- C9H28N3O15P5
- IUPAC Name:
- [(bis{2-[bis(phosphonomethyl)amino]ethyl}amino)methyl]phosphonic acid
- Test material form:
- not specified
Constituent 1
Study design
- Test substance input data:
- - Molar mass: 573.2
- Data temperature: 20˚C
- Water solubility: 500 000 mg/l
- Vapour pressure: 2.7E-09 Pa
- log Pow: -3.4 initially (minimum limit accepted by the software), although a surrogate value is preferred when the program used does not allow input of Koc (see below).
- Reaction half-life estimates for
- Air: assumed negligible
- Water: assumed negligible
- Soil: assumed negligible
- Sediment: assumed negligible
- Suspended sediment: assumed negligible
- Aerosols: assumed negligible
- Aquatic biota: assumed negligible - Environmental properties:
- As default
Results and discussion
Percent distribution in media
- Air (%):
- 0
- Water (%):
- 58.9
- Soil (%):
- 0
- Sediment (%):
- 41.1
Any other information on results incl. tables
Using a fugacity based model (Mackay level 1) DTPMP (15827-60-8) is predicted to migrate entirely to the aqueous compartment (100%) with 9E-5% in the soil, 6E-11% in air and 2E-06% in sediment.
However, in this model, Level 1 is modelling a very low soil and sediment adsorption, known not to be correct. Therefore further level 1 modelling using a substitute log Kow= 4.38 has been performed. This value of log Kow, set to obtain the correct Koc(9748) within the Level 1 program, gives:
Table: Level I outputs using an adjusted log Kow
Air |
3E-12% |
Soil |
93.5% |
Water |
4.4% |
Sediment |
2.1% |
The Level III program has also been applied, with the default model, using the same input parameters and the adjusted log Kow. The resulting distribution between compartments is as follows:
Table: Level III outputs using an adjusted log Kow
Distribution |
Release: 100% To air |
Release: 100% To water |
Release: 100% To soil |
% in air |
0% |
0% |
0% |
% in soil |
99.6% |
0% |
99.6% |
% in water |
0.24% |
58.9% |
0.23% |
% in sediment |
0.17% |
41.1% |
0.16% |
For the known use pattern, the most likely emission route will be directly to water. Direct emission to soil via spreading of sludge from waste water treatment plants is also possible.
The results reflect that most DTPMP found in air would be precipitated to soil, and that there is very little movement between soil and water, because transfer via the air compartment is very slow, for a substance of low volatility. In water, the adsorption coefficient of DTPMP results in significant adsorption to sediment.
The distribution in a sewage treatment plant has been estimated using the SimpleTreat model (implemented in EUSES 2.1.1) to be 0% degraded, 20% to water, 80% to sewage sludge. These outputs are based on non-biodegradability, and the properties given above for the fugacity-modelling of distribution. There is evidence from literature that wastewater treatment plants using a purification step with iron and aluminium salt additives to remove phosphorus, can be expected to achieve more than 90% removal of DTPMP, attributed largely to adsorption to amorphous precipitated iron oxides (Nowack, 2002). Measurements of one WWTP performance (Weil) showed a removal of 93%; another WWTP site showed 95% removal at the biological treatment stage with a further 2% removal at the flocculation (iron salts treatment) step.
Applicant's summary and conclusion
- Conclusions:
- Based on the relevant physical-chemical properties, the known use pattern (release to water) and the fact that it is non-biodegradable, DTPMP and its salts will partition primarily to water and suspended sediments. In the sewage treatment plant the substance is not expected to degrade, but will be removed on sewage sludge (80%) and be present in the effluent (20%).
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