Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 227-824-5 | CAS number: 5994-61-6
Endpoint summary
Administrative data
Description of key information
Skin irritation and Eye irritation studies were conducted according to recognized guidelines.
Chemical safety assement regarding respiratory irritation was done on the basis of observation of worker responses to high concentrations of airbourne dust containing high concentrations of N-(carboxymethyl)-N-(phosphonomethyl)glycine, originating/arising when handling the substance in the dry, pure form.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Additional information
As could be ecspected from the structure of N-(carboxymethyl)-N-(phosphonomethyl)glycine, containing several acidic functional groups, studies/experience has shown that the dry substance has pronounced corrosive and irritating properties when in contact with the eyes or the respirotory system, respectively. Skin irritation studies in rabbit has shown that the substance does not have acidic/corrosive/irritating propeties sufficient to be classified as corrosive or irritating to the skin.
Effects on eye irritation: corrosive
Effects on respiratory irritation: irritating
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
