Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 700-972-2 | CAS number: -
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 2020-2021
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- column elution method
- Remarks:
- slow stirring method
- Remarks on result:
- other: Testing planned
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From June 02, 2012 to August 21, 2012
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Principles of method if other than guideline:
- For surface active substances the critical micelle concentration (CMC) method is used as an alternative to the water solubility. The critical micelle concentration (CMC) is determined by measuring the surface tension of test substance solutions at different test substance concentration. For surface active substances which form micelles in solution, the surface tension decreases with increasing concentration until the CMC is reached. At concentrations above the CMC, the surface tension remains constant. The CMC is determined from a plot of the surface tension versus the logarithm of the test substance concentration.
- GLP compliance:
- yes
- Remarks:
- (OECD GLP)
- Type of method:
- other: critical micelle concentration (CMC)
- Water solubility:
- 1 mg/L
- Temp.:
- 20 °C
- Remarks on result:
- other: critical micelle concentration (CMC)
- Details on results:
- Test substance solutions at nominal concentrations of 1, 10, 100, 1000 and 10000 mg/L were prepared. Since a completely dissolved solution was not observed at any of the nominal concentrations, the surface tension could not be measured. Lower nominal concentrations cannot be used for this test. Based on these results, the CMC of the test substance was specified as < 1 mg/L.
- Conclusions:
- Under the conditions of the study, the water solubility (critical micelle concentration) of the test substance was determined to be <1 mg/L at 20°C ± 0.5°C
- Executive summary:
A study was conducted to determine the water solubility of the test substance, using CMC method according to GLP. Under the conditions of the study, the water solubility of the test substance was determined to be <1 mg/L at 20°C ± 0.5°C
Referenceopen allclose all
Description of key information
The water solubility was determined according to OECD Guideline 105 (Baltussen, 2012).
Further water solubility testing according to OECD Guideline 105 is planned.
Key value for chemical safety assessment
- Water solubility:
- 0.12 mg/L
- at the temperature of:
- 20 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
