Registration Dossier
Registration Dossier
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EC number: 931-251-2 | CAS number: -
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
- Bioaccumulation potential:
- low bioaccumulation potential
Additional information
The substance is a phthalate ester with linear C10 and C12 alkyl chains and is regarded as a High Molecular Weight Phthalate Ester (HMWPE) according to the definitions of the American Chemistry Council Phthalate Esters Panel HPV Testing Group (2001) and of the OECD (2004). This group includes chemically similar substances produced from alcohols having backbone carbon lengths of greater than C7. Due to their similar chemical structure, class members generally have similar physicochemical, biological toxicokinetic and toxicological properties or display an expected trend.
Data are not available for the assessment of the toxicokinetic properties of the C10 -C12 phthalate and read-across for toxicokinetic property assessment is therefore a possible approach to characterise toxicokinetic endpoints for the substance..
Various reviews of different phthalate esters by the Australian National Industrial Chemicals Notification and Assessment Scheme (NICNAS) are available. The data on the toxicokinetics indicate that phthalates in general are likely to be rapidly absorbed as the monoester from the gut and excreted via the urine.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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