Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
dermal absorption
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Value adopted by the European Commission in its Review report for the active substance 2,4-D; read across to the sodiumsalt.

Data source

Reference
Reference Type:
other: EU Review Report
Title:
Unnamed
Year:
2001
Report date:
2001

Materials and methods

Test guideline
Qualifier:
no guideline followed

Test material

Constituent 1
Reference substance name:
2,4-D
EC Number:
202-361-1
EC Name:
2,4-D
Cas Number:
94-75-7
IUPAC Name:
(2,4-dichlorophenoxy)acetic acid

Test animals

Species:
human

Results and discussion

Percutaneous absorption
Parameter:
percentage
Absorption:
ca. 2 %
Remarks on result:
other:

Applicant's summary and conclusion

Conclusions:
A dermal absorption of 2% will be used for human risk assessment and dermal DNEL derivation for the sodium salt of 2,4-D.