Registration Dossier
Registration Dossier
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EC number: 202-488-2 | CAS number: 96-20-8
Endpoint summary
Administrative data
Description of key information
Acute oral toxicity of 2-aminobutanol in the Rat
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 1 800 mg/kg bw
Additional information
The LD50 of DL 2 -aminobutanol in the rat is approximately 1800 mg/kg bw. There was no indication of the cause of death reported in the study.
There is no data available on the dermal and inhalation toxicity of 2 -aminobutanol. Due to the corrosivity of the substance this endpoint is waived according to the criteria in Column 2 of the REACH text, Annex VIII
Justification for classification or non-classification
Based on the Oral LD50 value, 2 -aminobutanol should be considered to be Harmful (R22) according to the dangerous substances directive, and Acute toxicity Category 4 according to GHS.
No classification for Dermal toxicity is proposed based on read across and the likelyhood that were such a test performed, the LD50 would be in excess of 2000 mg/kg bw.
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