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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Exposure related observations in humans: other data

Administrative data

Endpoint:
exposure-related observations in humans: other data
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: not personal measurements, but results of stationary measurements on the workplace

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2008
Report date:
2008

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
Tetramethylenediamine
EC Number:
203-782-3
EC Name:
Tetramethylenediamine
Cas Number:
110-60-1
Molecular formula:
C4H12N2
IUPAC Name:
butane-1,4-diamine

Method

Ethical approval:
not applicable
Details on study design:
During Turn Around activities at the DAB-fabriek the installation is opened up for maintenance activities.
During these maintenance activities potential exposure to1,4-di aminobutane (DAB) has been measured (local, stationary measurements in the air).
Exposure assessment:
measured

Results and discussion

Results:
All but one measurement were below the analytical detection level (0.01-0.03 mg/m3).
One measurement =0.03 mg/m3

Applicant's summary and conclusion

Conclusions:
All but one measurement were below the analytical detection level (0.01-0.03 mg/m3).
One measurement =0.03 mg/m3
These concentrations measured in areas where people work, are fare below the DNEL (7 mg/m3).
Executive summary:

During a turn around (maintenace activities) at the DAB plant, stationary measurements in air were performed.

All but one measurement were below the analytical detection level (0.01-0.03 mg/m3).

One measurement =0.03 mg/m3

These concentrations measured in areas where people work, are fare below the DNEL (7 mg/m3).