Registration Dossier
Registration Dossier
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EC number: 255-848-6 | CAS number: 42487-72-9
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- before 1992
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 1 994
Materials and methods
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 2-(diethylamino)-6-methyl-1H-pyrimidin-4-one
- EC Number:
- 255-848-6
- EC Name:
- 2-(diethylamino)-6-methyl-1H-pyrimidin-4-one
- Cas Number:
- 42487-72-9
- Molecular formula:
- C9H15N3O
- IUPAC Name:
- 2-(diethylamino)-6-methyl-1,4-dihydropyrimidin-4-one
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- oral: gavage
- Vehicle:
- propylene glycol
- Doses:
- 800, 1600, 2000 mg/kg
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 800 - < 1 600 mg/kg bw
- Based on:
- test mat.
Applicant's summary and conclusion
- Interpretation of results:
- harmful
- Remarks:
- Migrated information Criteria used for interpretation of results: OECD GHS
- Conclusions:
- The substance is found to have an oral LD50 between 800-1600 mg/kg bw, resulting in GHS classification in Cat 4, H302.
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